Research & Evidence

Written By Valerie Krossin

The evidentiary foundation for Class IV laser therapy / photobiomodulation is one of the most extensive in physical medicine, spanning basic science, animal studies, and human clinical trials.

Evidence at a Glance

Evidence Type

Volume / Finding

Total published studies (PBM/LLLT) > 12,000 publications 

Randomized Controlled Trials > 2,500 RCTs

PubMed entries (LLLT search, as of 2020) > 7,500 publications 

FDA Clearance - First cleared December 2003

Conditions with systematic review evidence

  • Knee OA

  • Neck pain

  • Back pain

  • Tendinopathy

  • TMD

  • Fibromyalgia

  • Neuropathy

  • Wound healing

  • Chronic pain


Valerie Krossin

As a nurse and educator with over 16 years of experience in the field of photobiomodulation (PBM), I have witnessed firsthand the transformative impact of this innovative therapy on pain, healing and sports recovery and performance enhancement. As the Educational Director and Senior Account Manager for industry leaders ASPEN Laser and TheraLight, I have been instrumental in forming strategic alliances with health professionals, businesses, individuals and professional and collegiate teams.

PBM harnesses the power of specific wavelengths of light, particularly in the red and near-infrared spectrum, to stimulate cellular processes such as ATP production, enhance mitochondrial function, reduce inflammation, promote tissue repair, and modulate biological responses like gene expression and ion channel activity. These benefits make near-infrared light a versatile tool in PBM, with applications ranging from athlete recovery and performance improvement and pain management to potential treatments for complex neurological conditions.

My unique perspective, combining over two decades of nursing experience with expertise in cutting-edge PBM technology, has allowed me to bridge the gap between clinical practice and sports medicine. This is evident in my recent work, including an abstract accepted by the American Society for Laser Medicine and Surgery (ASLMS) for E-Poster Presentation on Transcranial PBM for treating neurodegenerative diseases.

As the field of PBM continues to evolve, I remain committed to advancing its science and application in sports medicine. We are opening new frontiers in athletic performance and recovery, providing athletes with safe, effective, and non-invasive methods to optimize their potential.

https://www.photobiomodulation.expert
Previous

Safety & Contraindications
Next

Key Published Findings